Mihai G Netea Selected Research

Inflammasomes

1/2020	NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors: Results from the REPAIR consortium.
3/2016	Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases.
8/2015	Pathogenic NLRP3 Inflammasome Activity during Candida Infection Is Negatively Regulated by IL-22 via Activation of NLRC4 and IL-1Ra.
6/2015	Bone marrow-specific caspase-1/11 deficiency inhibits atherosclerosis development in Ldlr(-/-) mice.
5/2015	The interplay between inflammasome activation and antifungal host defense.
4/2015	Inflammasome inhibition: putting out the fire.
1/2015	Inflammasome-independent regulation of IL-1-family cytokines.
3/2014	IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans.
1/2013	Assessment of inflammasome activation in primary human immune cells.
1/2013	Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice.

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Mihai G Netea Research Topics

Disease

163	Infections 03/2024 - 01/2002
130	Inflammation (Inflammations) 02/2024 - 01/2002
63	COVID-19 03/2024 - 01/2020
61	Tuberculosis (Tuberculoses) 01/2024 - 02/2002
50	Sepsis (Septicemia) 01/2024 - 12/2002
33	Candidiasis (Moniliasis) 11/2022 - 01/2002
31	Atherosclerosis 01/2024 - 01/2002
27	Mycoses (Diseases, Fungus) 01/2023 - 01/2004
26	Neoplasms (Cancer) 03/2024 - 05/2009
25	Obesity 05/2024 - 06/2006
24	Rheumatoid Arthritis 01/2021 - 07/2003
20	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2019 - 08/2008
18	Aspergillosis 02/2024 - 01/2003
17	Insulin Resistance 01/2023 - 06/2006
15	Endotoxemia 10/2023 - 01/2002
15	Crohn Disease (Crohn's Disease) 01/2021 - 07/2004
14	Communicable Diseases (Infectious Diseases) 01/2022 - 01/2004
14	Q Fever (Fever, Q) 07/2019 - 06/2013
13	Lyme Disease (Disease, Lyme) 05/2024 - 06/2010
13	Candidemia 01/2023 - 08/2004
12	Pneumonia (Pneumonitis) 03/2024 - 01/2010
12	Necrosis 02/2024 - 01/2003
12	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 06/2015
11	Bacterial Infections (Bacterial Infection) 12/2023 - 01/2011
11	Respiratory Tract Infections (Respiratory Tract Infection) 10/2023 - 12/2012
10	Respiratory Insufficiency (Respiratory Failure) 03/2024 - 12/2013
10	Gout 02/2024 - 07/2012
10	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2023 - 07/2011
10	Human Influenza (Influenza) 08/2023 - 12/2015
9	Measles 01/2024 - 09/2013
9	Disease Progression 02/2023 - 11/2004
9	Fever (Fevers) 01/2023 - 01/2005
9	Poliomyelitis (Polio) 02/2022 - 03/2016
8	Virus Diseases (Viral Diseases) 12/2023 - 09/2011
8	Type 2 Diabetes Mellitus (MODY) 10/2020 - 09/2011
8	Systemic candidiasis 09/2017 - 08/2004
8	Chronic Granulomatous Disease 03/2014 - 01/2003
7	Malaria 01/2024 - 03/2009
7	Overweight 04/2023 - 01/2019
7	Septic Shock (Toxic Shock Syndrome) 01/2023 - 01/2002
7	Body Weight (Weight, Body) 01/2023 - 12/2003
7	Psoriasis (Pustulosis Palmaris et Plantaris) 11/2022 - 11/2010
7	Invasive Fungal Infections 03/2014 - 10/2004
6	Autoimmune Diseases (Autoimmune Disease) 01/2023 - 04/2002
6	Dysbiosis 01/2023 - 11/2016
6	Arthritis (Polyarthritis) 12/2022 - 09/2007

Drug/Important Bio-Agent (IBA)

185	CytokinesIBA 05/2024 - 01/2002
75	VaccinesIBA 01/2024 - 01/2010
36	Proteins (Proteins, Gene)FDA Link 02/2024 - 09/2003
35	InterleukinsIBA 01/2024 - 04/2002
31	Interleukin-6 (Interleukin 6)IBA 02/2024 - 01/2003
30	Biomarkers (Surrogate Marker)IBA 02/2024 - 11/2010
30	Pattern Recognition ReceptorsIBA 01/2019 - 11/2005
26	InflammasomesIBA 01/2020 - 02/2010
25	Interleukin-10 (Interleukin 10)IBA 03/2024 - 01/2003
25	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 03/2024 - 02/2006
25	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2020 - 01/2002
24	Interleukin-17 (Interleukin 17)IBA 02/2024 - 05/2010
24	Interleukin-1 (Interleukin 1)IBA 12/2022 - 09/2007
23	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2023 - 05/2002
23	Interleukin-18 (Interleukin 18)IBA 01/2021 - 04/2002
21	BCG Vaccine FDA Link 11/2023 - 12/2014
21	LigandsIBA 01/2023 - 07/2004
19	Interferon-gamma (Interferon, gamma)IBA 01/2023 - 12/2002
19	dectin 1IBA 01/2022 - 09/2009
18	InterferonsIBA 01/2023 - 04/2002
14	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 09/2014
13	Anti-Bacterial Agents (Antibiotics)IBA 05/2024 - 06/2009
13	RNA (Ribonucleic Acid)IBA 03/2024 - 01/2019
13	GlucansIBA 01/2024 - 01/2011
13	C-Reactive ProteinIBA 01/2023 - 02/2002
12	LipopolysaccharidesIBA 10/2023 - 04/2004
12	LipidsIBA 11/2021 - 11/2002
11	AntigensIBA 03/2024 - 03/2009
11	Uric Acid (Urate)IBA 02/2024 - 11/2010
10	Messenger RNA (mRNA)IBA 06/2023 - 02/2006
10	Toll-Like Receptor 4IBA 01/2015 - 07/2003
9	Attenuated VaccinesIBA 01/2024 - 10/2018
9	Lipoproteins (Lipoprotein)IBA 12/2023 - 04/2004
9	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2023 - 09/2007
9	NucleotidesIBA 09/2015 - 04/2006
8	LeptinIBA 09/2023 - 02/2002
8	Ferritins (Ferritin)IBA 01/2023 - 07/2012
8	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 11/2009
8	Interleukin-12 (IL 12)IBA 11/2022 - 04/2002
8	EndotoxinsIBA 11/2021 - 09/2005
8	CholesterolIBA 01/2020 - 02/2006
8	C-Type Lectins (C-Type Lectin)IBA 01/2020 - 03/2010
8	Caspase 1 (ICE Protease)IBA 01/2016 - 12/2009
7	ProteomeIBA 10/2023 - 10/2020
7	Histones (Histone)IBA 07/2023 - 04/2015
7	EnzymesIBA 01/2023 - 10/2014
7	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2022 - 02/2010
6	SteroidsIBA 02/2024 - 01/2019
6	Complement System Proteins (Complement)IBA 01/2023 - 11/2009
6	oxidized low density lipoproteinIBA 01/2022 - 02/2006
6	mouse dectin-2IBA 01/2022 - 03/2014
6	ChemokinesIBA 01/2022 - 05/2002

Therapy/Procedure

70	Therapeutics 04/2024 - 04/2003
32	Immunotherapy 03/2024 - 04/2004